The chemistry of opium

 Thebaine-Oxycodone, the Chemistry of Opium


In this blog article, the author discusses three main roles of thebaine - as a precursor to Oxycodone, in the creation of other narcotics like morphine and codeine, and in regulating body temperature. The author also provides a brief history as to how these chemicals came to be used in such a way.


What is thebaine?


Thebaine is a narcotic analgesic drug used primarily in the treatment of pain and cough. It is derived from opium and its chemical name is O-6-methyl-N-phenyl-7,8-dihydrocodeinone. Thebaine is one of the active metabolites of morphine produced by the body after it has broken down morphine into codeine.


How Does Oxycodone Work?


Order oxycodone online this is a highly potent narcotic opioid analgesic commonly prescribed for moderate to severe pain. Opiates are derived from thebaine, an alkaloid isolated in the opium poppy by Friedrich Sertürner in 1803. By binding to opioid receptors, oxycodone exerts its effects as it stimulates release of neurotransmitters such as dopamine, norepinephrine and serotonin. Oxycodone is used to treat moderate to severe pain. It may be given by mouth or as a transdermal patch that slowly When an individual takes oxycodone, the drug in the person's body will synthesize a morphine-like molecule called codeine. This is then broken down into heroin by the liver and/or intestines.


The History of Opium and Oxycodone


Opium and oxycodone are mirror images of each other. Oxycodone is the active drug in painkillers such as Percocet, which destroys endorphins and makes the person feel euphoric. Due to this, many people use opioid drugs recreationally and for their constipation problems. The history of opium and its derivatives is long and complex. The first mention of the use of opium dates back to ancient Assyria, where it was described as a plant that could induce sleep. It wasn't until the 1800s when it became popularized in Western culture with the introduction of the hypodermic needle.


The Benefits of Opioids


Opioid medications are a popular treatment for chronic pain. They help people without poisoning themselves or developing dependence. Unfortunately, the side effects of these drugs make them less effective over time and raise both risks of addiction and harm to the patient. However, there is a new class of opioid medication called thebaine-oxycodone that has been found to have fewer side effects than traditional opioids such as morphine and oxycodone.


Other Types of Opioids


There are many different types of opioids, and the chemistry used to make these drugs is complex. Some of the most well-known types include morphine, dihydromorphine, fentanyl, hydromorphone, oxycodone, methadone, buprenorphine, hydrocodone, codeine and tramadol.


Addiction to Opioids in Different Populations


Thebaine is a semi-synthetic opioid and oxycodone is an opiate found in the opium poppy, it is a natural alkaloid. Both opioids are found as white powdery substances, they are soluble in water.


Conclusion


There is a chemical similarity between thebaine and oxycodone that supports the idea that they are both derived from opium. Oxycodone is an opiate that is used to relieve pain, especially chronic pain. Thebaine was used in the past as a sedative and tranquilizer.

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